These effects, as with other vaccines, generally occur around the injection site. Engerix B is indicated for active immunisation against hepatitis B virus infection HBV caused by all known subtypes in non immune subjects. The seroprotection rates in subjects 20 years of age and above with type II diabetes were evaluated one month after the last dose of the primary vaccination and are presented in the Table below:.
Clinical particulars 4. Seroprotection rate.
With this schedule, a fourth dose should be administered at 12 months to assure long term protection as antibody concentrations after the third dose are lower than those obtained with the 0, 1, 6 months schedule. National recommendations on booster vaccination should be considered.
When available, hepatitis B immune globulins HBIg should be given simultaneously with Engerix B at a separate injection site as this may increase the protective efficacy. Population Schedule Seroprotection rate Healthy subjects 16 years of age and above 0, 1, 6 months at month 7: Consideration should be given to serological testing of those subjects who may be at risk of not achieving seroprotection following a complete course of Engerix B. Hepatitis B immunoglobulin can also be given at this time.
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Hepatitis B is an infectious disease, which causes the liver to become swollen inflamed. Hepatitis B vaccine, ATC code: Store in the original package. Months after the first vaccine dose: To view the changes to a medicine you must sign up and log in.
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In one clinical study conducted in children with the current formulation thiomersal free formulation , the incidence of pain, redness, swelling, drowsiness, irritability, loss of appetite and fever was comparable to the incidence observed in the clinical studies conducted with former thiomersal containing vaccine formulations. Often they do not show symptoms, and seem healthy for many years. It does not contain all the available information.